Metagenics Inflagesic — 30 Soft Capsules
TGA-listed practitioner-only analgesic and anti-inflammatory supplement with curcumin, BosPure Boswellia, and SPEEDTECH absorption technology.
Curcumin and BosPure Boswellia in a practitioner-only formula
Metagenics Inflagesic is a TGA-listed complementary medicine manufactured by Metagenics (Aust) Pty Ltd and formulated for the relief of musculoskeletal aches, pains, and inflammation.
It combines curcumin from turmeric with BosPure Boswellia, a patented high-potency Boswellia serrata extract, in a proprietary absorption-enhancing delivery system called SPEEDTECH.
The combination is marketed under the ingredient trademark Rhuleave-K and has been evaluated in published randomised controlled trials for acute musculoskeletal pain, osteoarthritis, and posture-related low back pain.
All published Rhuleave-K trials referenced in the source document were conducted or funded in association with the ingredient manufacturer. The studies are registered and peer reviewed, but independent replication would strengthen the evidence base.
Two complementary botanical actives
Curcumin — 133mg
Curcumin is the primary bioactive polyphenol extracted from turmeric. It influences multiple inflammatory pathways, including COX-1, COX-2, 5-LOX, and NF-kB, and also affects TRPV1 receptors involved in pain modulation.
Standard curcumin is poorly absorbed, which is why the SPEEDTECH delivery system is central to the formula.
BosPure Boswellia — 50mg
The standardised Boswellia serrata dry gum oleoresin extract is equivalent to 500mg of the original dry gum oleoresin.
BosPure is enriched in AKBA, an active boswellic acid associated with 5-LOX inhibition, while reducing levels of beta-boswellic acid found in lower-grade extracts.
A lipid matrix designed to improve absorption
SPEEDTECH is a micronisation technology that combines curcumin and boswellia extracts in a black sesame oil lipid matrix.
Because both curcumin and boswellic acids are fat-soluble and poorly absorbed in conventional capsule or powder form, the smaller particle size and lipid matrix are intended to improve dissolution and permeation across the gut wall.
Pain relief and anti-inflammatory support
- Provides analgesic and anti-inflammatory support through combined curcumin and boswellic acid activity.
- The SPEEDTECH delivery system is designed for faster absorption than standard botanical capsules or powders.
- Can be used for acute musculoskeletal pain flare-ups or ongoing anti-inflammatory support, according to the label directions.
- Free from dairy protein, lactose, eggs, gluten, wheat, nuts, yeast, and soy protein.
- Practitioner-formulated and GMP-manufactured with verified ingredient potency and purity.
What the referenced trials reported
The source document describes several registered randomised controlled trials evaluating the ingredient combination used in Inflagesic.
Acute exercise-induced pain
A 232-participant multicentre RCT reported a mean perceptible pain-relief onset of 68.5 minutes and meaningful relief at 191.6 minutes after a single 1,000mg dose.
Comparison with paracetamol
An 88-participant active-controlled study reported comparable pain-relief onset and magnitude between Rhuleave-K 1,000mg and paracetamol for acute musculoskeletal pain.
Posture-related low back pain
A 15-day placebo-controlled RCT in 52 participants reported improvement in Oswestry Disability Index scores with Rhuleave-K 500mg.
Mild to moderate osteoarthritis
A 12-week placebo-controlled study in 100 participants reported improvement in WOMAC scores beginning at six weeks.
An adjunct for symptom management
- Acute pain flare-ups: May provide an evidence-informed botanical option for short-term symptom relief between appointments.
- Patients who cannot use NSAIDs: May be considered where regular ibuprofen or naproxen is unsuitable, subject to medication and contraindication screening.
- Chronic inflammatory pain: May complement biomechanical treatment and rehabilitation in osteoarthritis or inflammatory tendinopathy.
- Post-adjustment soreness: May be considered for temporary soreness following treatment.
Follow the TGA-listed label directions
- Acute musculoskeletal pain: Take 2 soft capsules as a single dose.
- Ongoing inflammation: Take 2 soft capsules, 3 times daily, up to 6 capsules per day.
- Take with or after food to support absorption and reduce potential gastrointestinal sensitivity.
- Allow approximately 1 to 3 hours for onset of effect.
- Store below 30°C and keep out of reach of children.
- Use only as directed. If symptoms persist, consult your chiropractor or healthcare professional.
Important — please read before use
- Always read the label and follow the directions for use.
- Contains sesame seeds and sulfites. Do not use with a sesame or sulfite allergy.
- The capsule shell contains gelatin, so the product is not vegan.
- Curcumin and Boswellia may interact with anticoagulant or antiplatelet medication.
- Not recommended during pregnancy or breastfeeding without specific medical advice.
- This product is intended for symptom relief and is not a substitute for chiropractic or medical assessment.
- If symptoms are severe, worsening, or persistent, seek clinical assessment rather than increasing the dose.
